ISSN: 2155-9600
+32 25889658
Man-Tian Mi
Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Chongqing Key Laboratory of Nutrition and Food Safety,
IR Iran
Review Article
Effect of Curcumin on IL-6 and IL-8: A Meta-analysis and Systematic Review
Author(s): Suocheng Hui, Kai Liu, Xiaohui Zhu, Chao Kang and Man-Tian MiSuocheng Hui, Kai Liu, Xiaohui Zhu, Chao Kang and Man-Tian Mi
Background and objectives: Studies that have investigated the effects of curcumin on the levels of IL-6 and IL-8 are controversial. We performed this meta-analysis to quantitatively evaluate the effects of curcumin on IL-6 and IL-8 regulation.Methods and study design: The PubMed, Embase, and Cochrane Library (updated to March 2017) databases were searched for related studies. The pooled effects of curcumin treatment on IL-6 and IL-8 were evaluated using a random-effects model. Nine studies comprising a total of 512 subjects were included in the current meta-analysis.Results: The overall outcome of this meta-analysis suggested that curcumin had no favorable effects on the concentration of IL-6 (-0.80 pg/mL; 95% CI, -1.61 to 0.01 pg/mL; P=0.052). Compared with control subjects, subjects treated with curcumin did not.. View More»
DOI:
10.4172/2155-9600.1000697