ISSN: 2167-7948
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Maomei Ruan
Bolivarian Rep. of Venezuela
Research Article
Quantitative Radioiodine Treatment of Graves' Hyperthyroidism Using Different Intended Activities and the Same Weighting Factor
Author(s): Shiwei Sheng, Yang Wang, Maomei Ruan, Tao Ying and Libo Chen
Shiwei Sheng, Yang Wang, Maomei Ruan, Tao Ying and Libo Chen
Context: There is little consensus on the most appropriate dose regimen for radioiodine treatment (RIT) of Graves’ hyperthyroidism (GH), and quantitative studies on the role of the efficacy-affecting parameters are lacking.
Objective: This prospective study was designed to evaluate the feasibility of quantitative RIT of GH using a modified formula, which took into account eight parameters associated with the outcome.
Design: A 1-year follow-up study of 205 GH patients was performed.
The administered activity of 131I was established using a formula,
Activity MBq = [(gland weight (g) ×in tended activity) (MBq/g) /Max uptake] (% )× (1 + X/30) in which the X represented the sum of the parameters, and the administered activity increased or decreased by 1/30 when each of the parameters was prese.. View More»
DOI:
10.4172/2167-7948.1000157