Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

Marek Šebela

Marek Šebela
Department of Protein Biochemistry and Protemics, Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University, Šlechtitelu 11, CZ-783 71 Olomouc,
Czech Republic

Publications

  • Short Communication
    BIOSPEAN: A Freeware Tool for Processing Spectra from MALDI Intact Cell/Spore Mass Spectrometry
    Author(s): Martin Raus and Marek ŠebelaMartin Raus and Marek Šebela

    Here we introduce the software BIOSPEAN, which is applicable for processing of peptide/protein profiles obtained from MALDI intact cell/spore mass spectrometry. It has been developed as a web application using common technology. The BIOSPEAN automatically finds peaks in a mass spectrum. The peak detection principle involves a local scanning of intensity values around individual m/z positions. To cope with the level of noise, a threshold signalto- noise ratio is adjusted for filtering relevant results. Based on the detected peak pattern, a similarity search in a custom spectral database can subsequently be performed for sample identification. When a spectrum is analyzed by comparison with a database entry, a percentage score value is calculated from the number of identical peak positions found (they are assigned with an adjustable mass tolerance) divided by the number of all detected p.. View More»
    DOI: 10.4172/jpb.1000292

    Abstract PDF

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