Journal of Osteoporosis and Physical Activity
Open Access

Maria Orbetzova

Publications

• Research Article
  Bone Mineral Density in Bulgarian Patients with Type 1 Diabetes Mellitus
  Author(s): Nikolay Botushanov, Marianna Yaneva, Maria Orbetzova and Albena BotushanovaNikolay Botushanov, Marianna Yaneva, Maria Orbetzova and Albena Botushanova
  
  Aim of the study: To examine the bone mineral density (BMD) in Bulgarian patients with type 1 diabetes mellitus (DM) in comparison to age- sex- and ethnically matched healthy controls and its correlation with bone turnover markers: oteocalcin as a marker of bone formation and deoxypyridinoline cross-laps as bone resorption marker. Materials and methods: 162 patients with type 1 DM (97 females and 65 males) age 29.17 yrs. (20-40) and 200 (100 women and 100 men) age- and sex matched healthy controls were analyzed for BMD and Z-score of lumbar spine and femoral neck by dual X-ray absorptiometry (DXA) using Lunar DPX-A. Plasma levels of osteocalcin and urine levels of deoxypyridinoline cross-laps were determined. Results: BMD in type 1 DM showed statistically significant lower levels for lumbar spine L1-L4- men (1.2114 g/ .. View More»
  DOI: 10.4172/2329-9509.1000113

  Abstract PDF

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