ISSN: 2161-0665
+44 1478 350008
María Esther Martínez-Terán
France
Review Article
Multi-Particulate Dosage Forms for Pediatric Use
Author(s): María Esther Martínez-Terán, Thanh Huong Hoang-Thi and Marie-Pierre Flament
María Esther Martínez-Terán, Thanh Huong Hoang-Thi and Marie-Pierre Flament
In recent years, regulations on pediatric medicines have induced an increased need for research into novel child appropriate dosage forms. Indeed, children cannot be considered as « small adults » as they present different anatomical and physiological characteristics. Whatever the route of administration, the age-appropriateness of the formulation is of major importance and has to be taken into consideration. The development of new pediatric dosage forms encounters technical complexities such as dose modification, ease of administration/swallowing, tastemasking, chemical and physical stability, preservation, considerations of a multi-phase and/or multi-use product, packing, providing/designing the measuring device. Innovations are important and the research of new ways to deliver medicines tends to improve compliance, convenience and pharmacokinetic. Recently, the World Hu.. View More»
DOI:
10.4172/2161-0665.1000314