Advanced Techniques in Biology & Medicine
Open Access

María Guadalupe Ordaz Téllez

Publications

• Special Issue Article
  Assessment of the Genotoxic and Antioxidant Activities of Several Vegetables, Spices and Herbs in Combination with Cyclophosphamide and 4-Nitroquinoline n-Oxide in Drosophila Melanogaster
  
  Author(s): América Nixtin Castañeda Sortibrán, María Guadalupe Ordaz Téllez and Rosario Rodríguez Arnaiz América Nixtin Castañeda Sortibrán, María Guadalupe Ordaz Téllez and Rosario Rodríguez Arnaiz
  
  It has been demonstrated that the juices from several vegetables, spices and herbs protect against certain carcinogens. The antioxidant capacity of several vegetables has been documented. The aims of the present study were to evaluate the genotoxicity of celery, coriander, epazote, parsley and watercress using the Somatic Mutation and Recombination Test (SMART) on the wings of Drosophila melanogaster using Standard (ST) and High Bioactivation (HB) crosses with regular and high levels of metabolizing cytochrome P450 enzymes, respectively. The protective effects of the extracts against 4-Nitroquinoline n-Oxide (4NQO) 4NQO, an oxidant compound, and Cyclophosphamide (CP), an alkylating agent, were evaluated. Both promutagens were employed alone as positive controls and in combination with the extracts. The majority of the extracts were non-genotoxic, although several positive results were.. View More»
  DOI: 10.4172/2379-1764.S1-002

  Abstract

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