Journal of Clinical Toxicology
Open Access

Mariam Kachlek

Publications

• Research Article
  Individual and Combined Effects of Subchronic Exposure of Three Fusarium Toxins (Fumonisin B, Deoxynivalenol and Zearalenone) in Rabbit Bucks
  Author(s): Judit Szabó-Fodor, Mariam Kachlek, Sándor Cseh, Bence Somoskői, András Szabó, Zsófia Blochné Bodnár, Gábor Tornyos, Miklós Mézes, Miklós Mézes, Krisztián Balogh, Róbert Glávits, Dóra Hafner and Melinda Kovács Judit Szabó-Fodor, Mariam Kachlek, Sándor Cseh, Bence Somoskői, András Szabó, Zsófia Blochné Bodnár, Gábor Tornyos, Miklós Mézes, Miklós Mézes, Krisztián Balogh, Róbert Glávits, Dóra Hafner and Melinda Kovács
  
  Objective of the study was to determine reproductive toxicity of Fusarium toxins orally at three subchronic doses on adult Pannon White male rabbits. The four treatments were: control (C, toxin-free diet), F (5 mg/kg FB1), DZ (1 mg/kg DON+0.25 mg/kg ZEA), FDZ (5 mg/kg FB1+1 mg/kg DON+0.25 mg/kg ZEA) for 65 days (n=15/treatment). The doses were pre-determined according the EU limits in finished feed for young pig (in the absence of limits for rabbits’ feed; based on the European Commission Recommendation 2006/576/EC and the European Commission Directive 2003/100/EC). The most pronounced effects of the toxins were exerted on the reproductive processes. The ratio of spermatozoa showing progressive forward motility decreased (P<0.05) from 80% to 67% in the FDZ group by day 60. Differences were found between the groups DZ (66.3% ± 23.7) and C (80.2% ± 11.2) in sperma.. View More»
  DOI: 10.4172/2161-0495.1000264

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