Advanced Techniques in Biology & Medicine
Open Access
ISSN: 2379-1764
ISSN: 2379-1764
Massey W
Australia
Research Article
Insights into Functional Erythromycin/Antioxidant Containing Chitosan Hydrogels as Potential Bio-active Restorative Materials: Structure, Function and Antimicrobial Activity
Author(s): Perchyonok VT, Zhang S, Basson N, Grobler S,
Perchyonok VT, Zhang S, Basson N, Grobler S,
Substantial data are available in the literature on the role of Reactive Oxygen Opecies (ROS) and antioxidants in disorders such as the inflammatory and in chronic immune mediated conditions such as rheumatoid arthritis. However, remarkably little information is available on the periodontal diseases, which show many of the pathological features of other chronic inflammatory diseases. The periodontal tissues also provide an ideal medium within which to study mechanisms of ROS mediated tissue damage and of antioxidant defense in response to bacterial colonization, through the non-invasive collection of GCF. Bio-adhesive polymers appear to be particularly attractive for the development of alternative etches free dentin bonding system with an added advantage of additional therapeutic delivery systems to improve intradental administration of therapeutic and prophylactic agents if necessary.. View More»
DOI:
10.4172/2379-1764.1000116