Journal of Clinical and Cellular Immunology
Open Access

Matthias T

Publications

• Research Article
  Anti Enterocyte Autoantibodies in Pediatric Celiac Disease
  Author(s): Lerner A, Kushak RI, Jeremias P, Matthias T and Winter HS Lerner A, Kushak RI, Jeremias P, Matthias T and Winter HS
  
  Many aspects are shared between celiac disease and autoimmune enteropathy: symptoms, diagnosis by serological bio-markers, endoscopic findings, intestinal pathology, differential diagnosis, and pharmaceutical therapy in selected cases. Antibodies to tissue transglutaminase have been described in over 30% of patients with autoimmune enteropathy, but no anti-enterocyte antibodies were detected in a small population of pediatric celiac patients. The aim of the current study was to identify anti-enterocyte antibodies in pediatric patients with well-characterized celiac disease compared to a group of children with recurrent abdominal pain. Materials and methods: celiac disease (N=38) was diagnosed based on positive celiac serology (anti-neoepitope tissue transglutaminase (Aesku*) and/or anti endomysial antibodies) and small intestinal biopsy that was consiste.. View More»
  DOI: 10.4172/2155-9899.1000445

  Abstract PDF

Relevant Topics