Clinical & Experimental Cardiology
Open Access

Meng Li

Publications

• Research Article
  Telmisartan Protect Broiler Chickens from Pulmonary Arterial Remodeling Induced by Low Ambient Temperature
  Author(s): Xue-Qin Hao, Zhong-Min Wu, Shou-Yan Zhang, Meng Li, Tao Kong, Cong-Fu Huang and Xiang-Chao ChengXue-Qin Hao, Zhong-Min Wu, Shou-Yan Zhang, Meng Li, Tao Kong, Cong-Fu Huang and Xiang-Chao Cheng
  
  Objective: Renin-angiotensin system is associated with many vascular diseases. This study aims to explore the protective effect of telmisartan, Angiotensin type 1 receptor blocker, on pulmonary arterial remodeling induced by low ambient temperature in broiler chickens. Methods: Ninety chickens were randomly divided into 3 groups (n=30), including control group, low temperature group and telmisartan group. Chickens in low temperature group and telmisartan group were exposed to low ambient temperature from 14 days of age until 45 days of age; chickens in telmisartan group were gavaged with telmisartan 5 mg/kg once daily for thirty days. The pulmonary arterial systolic pressure was measured with right catheterization method. Wet lung weight index and right ventricular hypertrophy index wer.. View More»
  DOI: 10.4172/2155-9880.1000300

  Abstract PDF

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