Bipolar Disorder: Open Access
Open Access
ISSN: 2472-1077
+44 1478 350008
ISSN: 2472-1077
+44 1478 350008
Michelle Cho
Tanzania
Mini Review
The Impact of Drug and Gene Interaction on the Antipsychotic Medication for Schizophrenia
Author(s): Michelle Cho, Adriana Contreras, Ashley Garza, Samantha Olvera, David Castillo, Gabriel de Erausquin and Chun Xu*Michelle Cho, Adriana Contreras, Ashley Garza, Samantha Olvera, David Castillo, Gabriel de Erausquin and Chun Xu*
Objective: Schizophrenia, a neuropsychiatric disorder, is known to be neurodevelopmentally progressive. Due to the extensive interindividual variability found in the responses of patients, management of schizophrenia has proven to be challenging. This interindividual variability to treatment could be justified by the variation of the enzymes in charge of metabolizing medications, especially those associated with cytochrome P450. Since genetic factors influence the phenotypic responses to drugs, researchers are involved in identifying schizophrenic genetic factors, which could impact responses and severe effects for commonly known neuroleptic drugs known as pharmacogenetics. In order to predict drug response at the personal level, genetic variants that determine drug effects need to be identified.Methods: We have chosen to investigate gene target.. View More»
DOI:
10.4172/2472-1077.1000117