Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Michelle Mukonyora
Biotechnology Platform, Agricultural Research Council Private Bag X05,
Onderstepoort, 0110
South Africa
Review Article
A Review of Important Discontinuous B-Cell Epitope Prediction Tools
Author(s): Michelle MukonyoraMichelle Mukonyora
The identification of B-cell epitopes is imperative for the rational design of vaccines, diagnostics and immunotherapeutics. Several bioinformatics resources are freely available for the prediction of B-cell epitopes, however despite advances in recent years, they still possess limited predictive capabilities. The aim of this review is to highlight and describe the algorithms of the most widely used free B-cell epitope prediction resources. The reasons behind the limited predictive powers of these algorithms are also discussed... View More»
DOI:
10.4172/2155-9899.1000358