Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Mittal S
Pt BD Sharma Institute of Medical Sciences,
Rohtak, Haryana
India
Research Article
Comparing Weekly versus Three Weekly Schedules of Cisplatinum Concomitant with Radical Radiotherapy in Locally Advanced Carcinoma Uterine Cervix
Author(s): Mittal S, Chauhan A, Kaur P and Verma YPMittal S, Chauhan A, Kaur P and Verma YP
Aims and 0bjectives: To determine and evaluate the difference/s, in terms of tumor control and side effects, between weekly and three weekly cisplatin concomitant with radical course of radiotherapy for locally advanced carcinoma of cervix.
Materials and methods: The study was conducted on sixty previously untreated, histopathologically proven patients of locally advanced carcinoma of uterine cervix. The patients were treated with External Beam Radiotherapy (EBRT) 50Gy in 25 fractions over 5 weeks and concomitant cisplatin, followed by intra-cavity HDR brachytherapy (ICBT) 700cGy to point A, once in a week for three weeks. The patients were assigned randomly either of two groups of 30 patients each. In Group I (Study Group) the patients received three weekly cisplatin 75 mg/m2 for 2 cycles while in Group II (Control Group) the patients received.. View More»
DOI:
10.4172/2161-0932.1000423