ISSN: 2329-8901
Mónica De la Fuente
José Antonio Novais Street, 28040, Madrid
Spain
Research Article
Dietary Supplementation with Fermented Milk Containing Probiotics Improves Behaviour and Immune Response of Aged Mice
Author(s): Caroline Hunsche, Julia Cruces, Antonio Garrido, Oskarina Hernandez and Mónica De la FuenteCaroline Hunsche, Julia Cruces, Antonio Garrido, Oskarina Hernandez and Mónica De la Fuente
Aging is associated with an impairment of the regulatory systems, including the nervous and immune systems as well as the communication between them. The consumption of fermented milk containing live probiotic bacteria seems to have neurological and immunological benefits. The aim of the present study was to evaluate the effects of the supplementation with a fermented milk containing yogurt cultures and the probiotic Lactobacillus casei DN-114001 on behaviour and immune functions of old mice as well as on their life span. Also, the in vitro properties of these probiotics on functions of peritoneal leukocytes were analysed. Old female ICR-CD1 mice were supplemented with fermented milk containing probiotics. After 1 and 4 weeks of supplementation, behavioural tests were performed and immunological functions in peritoneal leukocytes studied. The results showed that a short-term (one week.. View More»
DOI:
10.4172/2329-8901.1000201