Journal of Leukemia
Open Access

Mohamed A Samra

Publications

• Research Article
  Comparable Outcome of Allogeneic versus Autologous Hematopoietic Peripheral Blood Stem Cell Transplantation in Acute Myeloid Leukemia Patients with Normal Karyotype and FLT3-ITD Negative
  Author(s): Hossam K Mahmoud, Alaa M ElHaddad, Omar A Fahmy, Mohamed A Samra, Raafat M Abdelfattah, Yasser H ElNahass, Hossam A ElAshtoukh, Gamal M Fathy and Fatma M ElRefaey Hossam K Mahmoud, Alaa M ElHaddad, Omar A Fahmy, Mohamed A Samra, Raafat M Abdelfattah, Yasser H ElNahass, Hossam A ElAshtoukh, Gamal M Fathy and Fatma M ElRefaey
  
  Introduction: Optimal post-remission treatment for acute myeloid leukemia patients with normal karyotype (AMLNK) in first complete remission (CR1) who lacks an HLA identical donor is still not well-defined. Aim of the Work: To compare the outcome of allogeneic versus autologous peripheral blood stem cell transplantation (PBSCT) in adult AML patients regarding toxicities of transplant procedure, transplant-related mortality (TRM), disease free survival (DFS) and overall survival (OS). Patients and Methods: 43 AML patients were included; 34 patients (with a median age 28 years) received myeloablative allogeneic PBSCT from a matched sibling donor while 9 patients (with a median age 36 years) received PBSC autograft. All patients had a normal karyotype (NK), FMS-like tyrosine kinase 3 .. View More»
  DOI: 10.4172/2329-6917.1000214

  Abstract PDF

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