Journal of Tumor Research
Open Access
ISSN: 2684-1258
ISSN: 2684-1258
Mohamed Ashour
Egypt
Research Article
Neutrophilic Lymphocytic Ratio as Predictive Biomarker in Advanced Rectal Cancer Patients
Author(s): Amrou Shabaan, Mohamed Ashour and Amany A ElbasmyAmrou Shabaan, Mohamed Ashour and Amany A Elbasmy
Background: Preoperative Neutrophil-Lymphocytic ratio has been suggested in many studies in resected colorectal cancer as predictive marker for recurrence and survival. This study investigated impact of pretreatment Neutrophil-Lymphocytic ratio on treatment outcome in rectal cancer patients.
Methods: Retrospective analysis of pretreatment Neutrophil-Lymphocytic ratio for one hundred and forty two patients with locally advanced rectal carcinoma (LARC) treated by neoadjuvant concomitant chemo-radiotherapy followed by surgical resection, between June 2006 and June 2011 in Minia University Hospital and Al-Hussein University Hospital. In order to study neutrophil lymphocytic ratio as a predictive factor for disease free survival and overall survival, other factors like age, sex, tumor length, tumor distance from anal verge, number of resected lym.. View More»
DOI:
10.35248/2684-1258.17.3.121