Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Mohamed Fathy Mostafa
Lecturer of Anesthesia and Intensive Care, Faculty of Medicine,
Assiut
Egypt
Research Article
Effect of Different Doses of Dexmedetomidine on Stress Response and
Emergence Agitation after Laparoscopic Cholecystectomy: Randomized
Controlled Double-Blind Study
Author(s): Mohamed Fathy Mostafa, Ragaa Herdan, Mohammed Yahia Farrag Aly and Azza Abo Elfadle
Mohamed Fathy Mostafa, Ragaa Herdan, Mohammed Yahia Farrag Aly and Azza Abo Elfadle
Background: Emergence agitation (EA) may develops during recovery from general anesthesia. It causes confusion, disorientation, and unpredictable behaviours. Surgical stress response activates the sympathetic nervous system and increase the release of catabolic hormones leading to prolonged hospital stay.
Objectives: We designed this study to assess the effect of different doses of intra-operative dexmedetomidine infusion on surgical stress response, emergence agitation and postoperative outcome.
Study design: A controlled double-blind study was conducted using a computer-generated randomization scheme.
Setting: The study was conducted in Assiut University Hospitals, Assiut, Egypt.
Methods: 90 patients scheduled for laparoscopic cholecystectomy were randomly ass.. View More»
DOI:
10.4172/2155-6148.1000707