Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Research Article
Intravenous versus Ultrasound Guided Thoracic Paravertebral Morphine-Dexmedetomidine Combination in Patients with Multiple Rib Fractures
Author(s): Mona Mohamed Mogahed, Eman Ramadan Salama, Mohamed Shafik Mohran Elkahwagy
Mona Mohamed Mogahed, Eman Ramadan Salama, Mohamed Shafik Mohran Elkahwagy
Background: Severe pain caused by multiple rib fractures (MRF) can compromise oxygenation, ventilation and pulmonary functions so can affect patient outcome. Adequate pain control helps to avoid these complications. Thoracic paravertebral analgesia is comparable to thoracic epidural with fewer side effects.
Methods: Seventy-five patients were randomly allocated into three groups, (n=25 each). Group (GM) received intravenous morphine with a loading dose of 0.1-0.2 mg/kg followed by PCA bolus of 1mg with a six min lockout. Group (GMD) received also intravenous morphine with a loading dose of 0.1-0.2 mg/kg then PCA bolus of 1 mg morphine plus 5 μg dexmedetomidine with a six min lockout. Group (GPV) received paravertebral morphine loading dose of 0.2 mg/kg then PCA bolus of 0.1 ml/kg of a solution with a concentration of 0.5 mg/ml morphine mixed.. View More»
DOI:
10.4172/2155-6148.1000786