Journal of Hematology & Thromboembolic Diseases
Open Access
ISSN: 2329-8790
+44 1478 350008
ISSN: 2329-8790
+44 1478 350008
Mohammed AL-Nuzaily
Yemen
Research Article
Von Willebrand Factor: A Novel Marker of Endothelial Dysfunction in Clinical Hyperthyroidism Patients
Author(s): Mohammed AL-Nuzaily, Lutfi AL-Maktri, Saleh Bamashmoos, Samir Taresh and Faisal AliMohammed AL-Nuzaily, Lutfi AL-Maktri, Saleh Bamashmoos, Samir Taresh and Faisal Ali
Hyperthyroidism is associated with altered endothelial dysfunction and increased risk of arterial thromboembolism and cardiovascular disease. Von Willebrand factor (vWF) is a marker of endothelial dysfunction. There is controversy in reports that have been published concerning the concentrations of vWF in hyperthyroidism. The aim of this study was to investigate the plasma vWF levels in clinical hyperthyroid patients, as well as its relationship to thyroid hormones fT3, fT4 and TSH compared to control subjects. In this study forty recently diagnosed, non-treated clinical hyperthyroid patients (f=37, m=3) and twenty normal volunteers control (f=18, m=2) were included, and subjected to determination of p.. View More»
DOI:
10.4172/2329-8790.1000115