ISSN: 2167-0412
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Moussa Ahmed
Pharmacognosy and Api-Phytotherapy Research Laboratory,
Algeria
Research Article
Preliminary Investigation on Antimycotic Synergism of Raw Honey and Essential Oil of Thyme (Thymus vulgaris L.)
Author(s): Moussa Ahmed, Saad Aissat, Abdelmelek Meslem and Noureddine Djebli
Moussa Ahmed, Saad Aissat, Abdelmelek Meslem and Noureddine Djebli
Aims: Several natural products have exhibited synergistic activity against microorganisms. In this study we
investigated the existence of synergistic antifungal effect between Thyme (Thymus vulgaris L.) essential oil and different varieties of raw honey from Algeria.
Methodology: To evaluate antimycotic effects of mixtures of raw honey (RH) and Thymus vulgaris oil (TVO)
using agar disc diffusion assay. The antimycotic capacity was determined against two pathogenic yeasts clinical isolates Candida albicans and Rhodotorula mucilaginosa.
Results: The results indicated that the essential oil of TVO and raw honey are efficient against the tested
yeasts. The diameters of inhibition Zone (DIZ) values were all between 8.26-9.5 mm for the RH and between
8.56-10.3 mm for the TVO. RH and TVO interacted synergistically to inhibit Candida albicans and Rhod.. View More»
DOI:
10.4172/2167-0412.1000177