Pharmaceutical Analytical Chemistry: Open Access
Open Access
ISSN: 2471-2698
+44 1478 350008
ISSN: 2471-2698
+44 1478 350008
Naik KK
India
Research Article
Development and Validation of a New Chromatographic Method for the
Simultaneous Estimation of Serratiopeptidase, Aceclofenac and Paracetamol
by RP-HPLC
Author(s): Navneet Kumar U, Afroze A, Pradeepti C, Shailendra K, Naik KK, Sharma M, Swati P, Sunil T and Sameer SNavneet Kumar U, Afroze A, Pradeepti C, Shailendra K, Naik KK, Sharma M, Swati P, Sunil T and Sameer S
Background: Method development, validation is an important parameter for the simultaneous estimation of Serratiopeptidase (SERA), Aceclofenac (ACE) and Paracetamol (PCM) by RP-HPLC, is supposed to be a costly and tedious process. The present study revealed using cheap and cost effective solvent system for the simultaneous estimation of Serratiopeptidase (SERA), Aceclofenac (ACE) and Paracetamol (PCM).
Objective: Development and validation of a new chromatographic method for the simultaneous estimation of Serratiopeptidase (SERA), Aceclofenac (ACE) and Paracetamol (PCM) by RP-HPLC of marketed formulations.
Methods: Simultaneous determination of SERA, ACE and PCM were carried out by RP-HPLC at the wavelength 327 nm, flow rate 0.4 mL/min, and the mobile phase used was water: methanol in the ratio (50:50 v/v). Further .. View More»
DOI:
10.4172/2471-2698.1000122