ISSN: 2167-7700
+44 1223 790975
Naito T
Japan
Research Article
Effect of Second-Line Chemotherapy in Elderly Patients with Non-Small Cell
Lung Cancer
Author(s): Kobayashi H, Kenmotsu H, Suzuki K, Omori S, Nakashima K, Wakuda K, Ono A, Naito T, Murakami H, Endo M, OhdeY and Takahashi T
Kobayashi H, Kenmotsu H, Suzuki K, Omori S, Nakashima K, Wakuda K, Ono A, Naito T, Murakami H, Endo M, OhdeY and Takahashi T
Background: The effect of second-line chemotherapy in patients with non-small cell lung cancer (NSCLC) who received first-line chemotherapy at the age of ≥ 75 years is unclear.
Methods: Sixty-five elderly patients with NSCLC who received first-line chemotherapy at the age of ≥ 75 years and treated with second-line chemotherapy at Shizuoka Cancer Center between January 2005 and December 2014 were retrospectively reviewed.
Results: The overall response rate of the second-line chemotherapy was 9.2% [95% confidence interval (CI) 4-19]. The median progression-free survival at the second-line chemotherapy was 2.2 months. The median overall survival at the second-line chemotherapy was 7.5 months. Multivariate analysis of prognostic factors showed that an Eastern Cooperative Oncology Group performance-status score (P.. View More»
DOI:
10.4172/2167-7700.1000236