Journal of Hematology & Thromboembolic Diseases
Open Access

Nélson Domingues

Publications

• Short Communication
  Treatment Outcomes of Patients with Primary Mediastinal Diffuse Large B-Cell Lymphoma: A Single-Center Experience
  Author(s): Márcio Tavares, Ana Margarida Simas, Carla Castro, Ana Espírito Santo, Nélson Domingues, Isabel Oliveira, Ângelo Martins, Ilídia Moreira, Luísa Viterbo, Ângelo Oliveira, Rui Henrique, Sérgio Chacim and José Mário MarizMárcio Tavares, Ana Margarida Simas, Carla Castro, Ana Espírito Santo, Nélson Domingues, Isabel Oliveira, Ângelo Martins, Ilídia Moreira, Luísa Viterbo, Ângelo Oliveira, Rui Henrique, Sérgio Chacim and José Mário Mariz
  
  Background: Primary mediastinal B-cell lymphoma (PMBCL) is a distinct clinicopathologic entity from diffuse large B-cell lymphoma. The optimal first-line therapy for PMBCL is subject of ongoing debate with no accepted standard of care. Patients and Methods: We searched retrospectively for adult patients with newly diagnosed PMBCL treated at our department between 2002 and 2014. Clinical, management and follow-up data were collected. Staging and response assessment of patients included PET and/or CT scan. Results: Twenty-nine patients with PMBCL (17 female and 12 male) were included. The median age at diagnosis was 36 years (18-79 years). Eighteen (62.1%) and 20 (69%) patients had limited-stage and bulky disease, respectively. All patients were treated with rituximab-based combination chemotherapy; 21 patients underwent.. View More»
  DOI: 10.4172/2329-8790.1000221

  Abstract PDF

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