Journal of Alcoholism & Drug Dependence
Open Access

Nibedita Naha

Publications

• Review Article
  Toxic Exposure and Life Style Factors on Ageing Brain Neurodegenerative Disease, Alzheimer’s and Parkinson’s: Role of Natural Antioxidants to Ameliorate the Condition
  Author(s): Nibedita Naha, Moitreyi Das, Arnab Banerjee Nibedita Naha, Moitreyi Das, Arnab Banerjee
  
  Toxic exposure is a major risk factor for many neurodegenerative diseases in ageing brain such as, Alzheimer’s (AD) and Parkinson’s (PD), where decline of biological activities in cellular microenvironment render the organism more susceptible to either endogenous or exogenous stressors especially free radical damage, leading to pathological conditions. PCBs, MPTP, organochlorines and organophosphates, paraquat, fipronil, pyrithroid, quinines, and metals like, lead, cadmium, chromium, cobalt, manganese, arsenic etc. are play the crucial role in age-related diseases, AD and PD. Further, the degree of changes in the ageing brain in these cases not only depends on toxic exposures and genetic susceptibility but also on food habit, life style (use of alcohol, smoking, caffeine), environment etc. Certain antioxidants through diet can improve scenario of ageing brain and modulate .. View More»
  DOI: 10.4172/2329-6488.1000309

  Abstract PDF

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