Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Nihad Shoukry Shoeib
Egypt
Dr. Nihad Shoukry Shoeib is a distinguished physician in the Internal Medicine and Endocrinology Department at the Faculty of Medicine, Ain Shams University, Egypt. Her clinical expertise and research focus on the interplay between endocrine disorders and neurological conditions. In 2018, Dr. Shoeib co-authored a pivotal study titled "Evaluation of Thyroid Functions in Patients with Multiple Sclerosis Before and After Treatment with Interferon Beta," published in the Journal of Thyroid Disorders & Therapy. This prospective study investigated the impact of interferon beta therapy on thyroid function and autoimmune thyroid markers in patients with multiple sclerosis (MS). The research involved 50 newly diagnosed MS patients and 50 healthy volunteers, assessing thyroid function tests and autoimmune markers before and six months after initiating interferon beta treatment. The findings revealed a significant increase in anti-thyroid peroxidase and anti-thyroglobulin antibody levels post-treatment, indicating that interferon beta therapy can induce thyroid autoimmunity in MS patients. This underscores the importance of regular monitoring of thyroid function and autoimmunity markers in MS patients undergoing interferon beta therapy to ensure timely detection and management of potential thyroid dysfunctions.
Research Article
Evaluation of Thyroid Functions in Patients with Multiple Sclerosis Before and after Treatment with Interferon Beta
Author(s): Magda Shokry Mohammed, Nihad Shoukry Shoeib, Inas Mohammed Sabry, Dina Mohammed Abd El Gawad, Ahmed Mohamed Bahaaeldin and Nahla Nader Adly
Magda Shokry Mohammed, Nihad Shoukry Shoeib, Inas Mohammed Sabry, Dina Mohammed Abd El Gawad, Ahmed Mohamed Bahaaeldin and Nahla Nader Adly
Background: Multiple sclerosis (MS) is a multi-component disease characterized by inflammation, neurodegeneration and failure of central nervous system (CNS) repair mechanisms. Autoimmune thyroid disease is a frequently studied disorder in MS, most studies have focused primarily on the increased prevalence of thyroid dysfunction and anti-thyroid antibodies (ATAs) in MS patients compared with a control population.
Objectives: To investigate the effect of treatment with interferon beta on thyroid functions and autoimmune thyroid markers in patients with multiple sclerosis.
Subjects and Methods: This prospective study was conducted on 100 subjects recruited from the inpatient and outpatient clinic of Internal Medicine department and Neurology Unit of Ain Shams University Hospitals. They were divided into group 1, whic.. View More»
DOI:
10.4172/2167-7948.1000227