ISSN: 2161-1017
+44 1478 350008
Nilufer Ozdemir Kutbay
Turkey
Research Article
Low Levels of Cystatin C in Patients with Acromegaly
Author(s): Banu Sarer Yurekli and Nilufer Ozdemir KutbayBanu Sarer Yurekli and Nilufer Ozdemir Kutbay
Background: Cyst C is a cysteine protease inhibitor produced by all nucleated human cells. Studies show that Cyst C levels are associated with increased risk of cardiovascular events.
Aim: We aimed to figure out Cyst C levels in acromegaly patients and to compare with control subjects who don’t have acromegaly.
Methods: Forty-five subjects (24 female, 21 male, mean ages of 48.4 ± 10.3) with acromegaly and 37 gender and age matched subjects (25F, 12 M, mean ages of 50.0 ± 8.0) as control group were recruited. Acromegaly patients were classified into two groups as active acromegaly (AA, n=28) and controlled acromegaly (CA, n=17). Demographic, anthropometric and laboratory values were recorded. Framingham Coronary Heart Disease Risk Score was used to estimate risk of heart attack in 10 years. Frami.. View More»
DOI:
10.4172/2161-1017.1000290