Journal of Clinical and Experimental Ophthalmology
Open Access

Nursen Düzgün

Publications

• Research Article
  Efficacy of Infliximab in Patients with Refractory Uveitis Associated with Behcet Disease
  Author(s): Nilufer Yalcındag F, Ozge Yanık and Nursen DuzgunNilufer Yalcındag F, Ozge Yanık and Nursen Duzgun
  
  Background: Ocular involvement in Behçet disease is responsible for severe morbidity by causing nongranulomatous panuveitis and retinal vasculitis. In some cases, recurrent attacks cannot be controlled by conventional immunosuppressives and corticosteroid or interferon. The aim of this study is to investigate the efficacy of infliximab treatment in patients with refractory uveitis associated with Behçet disease.Methods: Nine patients with Behçet disease related uveitis were included in the study. Uveitis had been refractory to treatment with either a combination of cyclosporine-A, azathioprine, and corticosteroid or interferon α-2a monotherapy in all patients. Patients received infliximab infusions (5 mg/kg) at weeks 0, 2, 6, and every 8 weeks thereafter. In patients receiving interferon α-2a at the time of initiation of.. View More»
  DOI: 10.4172/2155-9570.1000319

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