ISSN: 2167-0412
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Obeagu Emmanuel Ifeanyi
Nigeria
Research Article
Effect of Luffa cylindrica Leaf Extract on Hematological Parameters of Swiss Albino Mice
Author(s): Emmanuel Asuquo Etim*, Yusuf Abdulhakeem Adebayo and Obeagu Emmanuel IfeanyiEmmanuel Asuquo Etim*, Yusuf Abdulhakeem Adebayo and Obeagu Emmanuel Ifeanyi
Background: Luffa cylindrica is a tropical fibrous flowering plant used in folkloric medicine. This study aims to examine the effect of methanolic leaf extract of Luffa cylindrica on hematological parameters of Swiss albino mice. Materials and methods: 70 adult mice of both sexes with mean weight of 22 ± 5 g were used for this study. Luffa cylindrica leaves was pulverized to coarse powder from where methanolic extract was obtained. 0.2 ml of 50 mg/kg, 100 mg/kg, and 200 mg/kg respectively of leaf extract was administered to mice for four days. After administration, 1 ml of blood was collected from each mice through cardiac puncture into EDTA bottle for full blood count estimation using Abacus-80 hematological analyzer. Results: The administration of 50 mg/kg, 100 mg/kg and 200 mg/kg doses of the extract resulted in increased lymphocyte count from .. View More»
DOI:
10.4172/2167-0412.1000318