Journal of Proteomics & Bioinformatics
Open Access

Oindrila Paul

Publications

• Research Article
  The Effect of Oxygen on Bile Resistance in Listeria monocytogenes
  Author(s): Morgan L Wright, Ken Pendarvis, Bindu Nanduri, Mariola J Edelmann, Haley N Jenkins, Joseph S Reddy, Jessica G Wilson, Xuan Ding, Paul R Broadway, Mais G Ammari, Oindrila Paul, Brandy Roberts and Janet R Donaldson Morgan L Wright, Ken Pendarvis, Bindu Nanduri, Mariola J Edelmann, Haley N Jenkins, Joseph S Reddy, Jessica G Wilson, Xuan Ding, Paul R Broadway, Mais G Ammari, Oindrila Paul, Brandy Roberts and Janet R Donaldson
  
  Listeria monocytogenes is a Gram-positive facultative anaerobe that is the causative agent of the disease listeriosis. The infectious ability of this bacterium is dependent upon resistance to stressors encountered within the gastrointestinal tract, including bile. Previous studies have indicated bile salt hydrolase activity increases under anaerobic conditions, suggesting anaerobic conditions influence stress responses. Therefore, the goal of this study was to determine if reduced oxygen availability increased bile resistance of L. monocytogenes. Four strains representing three serovars were evaluated for changes in viability and proteome expression following exposure to bile in aerobic or anaerobic conditions. Viability for F2365 (serovar 4b), EGD-e (serovar 1/2a), and 10403S (serovar 1/2a) increased following exposure to 10% porcine bile under anaerobic conditions .. View More»
  DOI: 10.4172/jpb.1000396

  Abstract PDF

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