Journal of Drug Metabolism & Toxicology
Open Access

Ola N Sayed

Publications

• Research Article
  Protective Effect of Rosemary (Rosmarinus officinalis) Extract on Lithium-Induced Renal and Testis Toxicity in Albino Rats
  Author(s): Marwa A Mwaheb, Ola N Sayed and Safaa H Mohamed Marwa A Mwaheb, Ola N Sayed and Safaa H Mohamed
  
  Lithium is used common as an effective drug for the medication of many psychiatric disorders in human. The current study was proceed to analysis the protective effect of rosemary leaves extract on renal and testis toxicity induced by Lithium in rats. Forty adult Albino male rats were divided into four equal groups. Group (I) was kept on standard rodent chow and served as healthy control group, Group (II) were orally administrated with 220 mg/kg/day of rosemary extraction, group (III) were orally administrated with 100 mg/kg/day of lithium carbonate (Li2CO3) and Group (IV) were orally administrated with both 220 mg/kg/day rosemary extraction and 100 mg/kg/day (Li2CO3). All groups were treated for 4 weeks. Lithium caused significant increase in plasma Malondialdehyde (MDA), creatinine, urea, Neuron Specific Enolase (NSE) and Human Chorionic Gonadotropin (HCG) levels, and while, signific.. View More»
  DOI: 10.4172/2157-7609.1000216

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