Journal of Applied Pharmacy
Open Access

Pandya DR

Publications

• Research Article
  Synthesis Characterization and Biological Influence of Some Newly Synthesized Mix ligand Chelates
  Author(s): Pandya DR Pandya DR
  
  Objective: A series of mixed ligand chelates of d10 were synthesized expending 3TC a potent nucleoside analogue and ACV, is a guanosine analogue antiviral drug. Methods: The synthesized chelates were characterized by IR, Mass spectra, TGA analysis and Elemental analysis and were evaluated for their anti-fungal activity against a panel of two pathogenic fungal strains namely, Aspergillus niger, and Candida albicans by Broth-dilution method, antibacterial activity against E. coli, P. aeruginosa, S. aureus, S. pyogenus. Results: All the compounds showed significant inhibitory activity against the microorganism. Anti-bacterial activity was determined using Ampicillin as a standard and antifungal activity was determined using standard Greseofulvin. Conclusion: Out of all the chelates, the chel.. View More»
  DOI: 10.4172/1920-4159.1000219

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