Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Patil MB
University Department of Biochemistry,
L.I.T. Premises, R.T.M. Nagpur University, Nagpur
India
Research Article
Potential In vivo Immunomodulatory Effects of the Most Active Lectin Isolated from Seeds of Zizyphus oenoplia
Author(s): Butle A, Talmale S and Patil MB
Butle A, Talmale S and Patil MB
Objective: Lectins are complex and heterogenous group of carbohydrate binding proteins, commonly found in all types of organisms with striking biological activities. Many anti-inflammatory synthetic medicines are available, but they show many side effects. In this context, anti-inflammatory compounds free from any adverse effects are the requirement of time. In the present study, the most active lectin isolated from seeds of Zizyphus oenoplia is tested for its anti-allergic and anti-inflammatory activities.
Methods: The most active lectin was isolated from seeds of Zizyphus oenoplia. The procedure of isolation involved extraction of lectins from dried seeds in sodium phosphate buffered saline (0.02 M, pH 7) followed by precipitation with ammonium sulphate (20%-60%) and dialysis. Later, affinity chromatography and ion-exchange chromatography .. View More»
DOI:
10.4172/2155-9899.1000386