Journal of Bone Research
Open Access

Peng Hu

Publications

• Research Article
  A Single Nucleotide Polymorphism in the GDF5 Gene (rs143383) may contribute to the Increased Risk of Osteoarthritis and Lumbar Disc Degeneration: an Updated Meta-Analysis
  Author(s): Liying Jiang, Yidan Wang, Xiaoyue Zhu, Peng Hu, Dandong Wu and Aidong Liu Liying Jiang, Yidan Wang, Xiaoyue Zhu, Peng Hu, Dandong Wu and Aidong Liu
  
  Background: Although previous studies have investigated the association between GDF5 polymorphism rs143383 and osteoarthritis (OA) or lumbar disc degeneration (LDD), the results were inconsistent. Given the availability of more recent data, we performed a meta-analysis to access the association between GDF5 polymorphism rs143383 and OA or LDD as well as whether the association vary by ethnicity, sex, study design and disease sites. Method: Published literature from PubMed, Embase, SCOPUS, Google Scholar, and China National Knowledge Infrastructure (CNKI) databases were retrieved. ORs and 95%CIs were calculated to estimate the strength of the association between the GDF5 polymorphism rs143383 and the risk of OA or LDD. Results: A total of 15 articles containing 33 studies were enrolled in this meta-analysis. Overall.. View More»
  DOI: 10.4172/2572-4916.1000183

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