Journal of Osteoporosis and Physical Activity
Open Access

Ping-Chung Leung

Publications

• Commentary
  Current Status of Potent Bone Resorption Antagonists
  Author(s): Ping-Chung LeungPing-Chung Leung
  
  Since osteoporosis is considered as an important risk factor to the development of bone fractures, the search for effect therapeutic agents for its prevention and maintenance has never stopped. From hormonal replacement, promotion of bone formation, to prevention of bone resorption has all been tried. The most active part has been played by the antiresorptive agents, viz the Bisphosphonates. Large investments in research have increased the potency of the drug hundreds of folds and remarkably secured a very effective patient compliance to once a year injection. The therapeutic triumph is complicated with serious though infrequent adverse effects with prolonged or high dose administrations. It is therefore appropriate time to realize the exact safety, the favorable dosages, and the duration of treatment of bisphosphonates. Several extended studies on bisphosphonates have given t.. View More»
  DOI: 10.4172/2329-9509.1000129

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