Journal of Proteomics & Bioinformatics
Open Access

Pratap D

Publications

• Research Article
  Comparative Network Analysis of Two-Component Signal Transducing Protein-Protein Interactions in Enterococcus faecalis Sp.
  Author(s): Ranjith N. Kumavath and Pratap D Ranjith N. Kumavath and Pratap D
  
  Background: Protein-Protein interactions network analysis of Enterococcus faecalis sp. in a comparative approach helps for the dissection of gene function, potential signal transduction, and virulence  pathways. Our research shed light on the comparative network analysis of two component signal transducing protein-protein interactions in ten different Enterococcus faecalis strains on the base of protein interactions prediction analysis and Host-Pathogen Interactions analysis using STRING and HPIDB databases. Around 30-40 proteins participate in the Two Component System of Enterococcus faecalis. Results: The network parameters of protein-protein interactions were calculated. The topological coefficient of almost all the strains of Enterococcus faecalis network perfectly followed a power law distribution (correlation) 1.000; R-squared) 1.00.. View More»
  DOI: 10.4172/jpb.1000249

  Abstract PDF

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