Journal of Alcoholism & Drug Dependence
Open Access
ISSN: 2329-6488
ISSN: 2329-6488
Qi K Zuo
Tanzania
Review Article
Cannabinoids in Opioid Addiction Treatment: Pharmacological Mechanisms
Author(s): Qi K Zuo, Kelsey L Tam, Alex Bekker, Wanhong Zuo and Jiang-Hong YeQi K Zuo, Kelsey L Tam, Alex Bekker, Wanhong Zuo and Jiang-Hong Ye
Opioid addiction, a chronic relapsing disorder, continues to impose great health and economic burden on our society. America’s opioid crisis has become an epidemic due in part to the lack of effective treatments for the negative physical and emotional states suffered by the individuals during withdrawal from chronic opioid use. These symptoms might be major contributing factors to relapse. Recently, Cannabis and cannabinoids have emerged as a potential therapeutic strategy in the treatment of opioid addiction. This review differs from many other reports in the field by focusing on the possible mechanisms underlying the effects of cannabinoids on the negative physical and emotional states induced by opioid withdrawal. We start by briefly outlining the current opioid crisis and how both opioids and cannabinoids affect the mammalian central nervous system (CNS). Next, we p.. View More»
DOI:
10.35248/2329-6488.19.7.325