Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Raffaele Landolfi
Italy
Review Article
Role of Fecal Calprotectin in Monitoring Response to Therapy in Inflammatory Bowel Diseases
Author(s): Antonella Gallo, Antonio Gasbarrini, Giovanna Passaro, Raffaele Landolfi and Massimo MontaltoAntonella Gallo, Antonio Gasbarrini, Giovanna Passaro, Raffaele Landolfi and Massimo Montalto
Inflammatory bowel diseases (IBDs) are chronic intestinal disorders characterized by a typically relapsing course. Disease flares occur in a random way and are often unpredictable. In search to provide noninvasive, cheap and rapid methods able to help in diagnosis and monitoring of IBD activity, within the last years, fecal neutrophil-granular proteins, like calprotectin, have been largely studied. Different studies showed a good diagnostic accuracy of fecal calprotectin (FC) in IBDs and a close correlation between levels of this marker and degree of IBD activity.More recently, emerging interest has rising on the role of FC in assessing response to therapy and predicting relapse in IBD. We performed a MEDLINE search for more recent articles published on this topic. Encouraging results show that FC represents a reliable monitoring tool to assess response to treatment, signi.. View More»
DOI:
10.4172/2155-9899.1000252