ISSN: 2155-6148
Raghavendra Rao
India
Research Article
Comparison of the Effectiveness of Unimodal Opioid Analgesia with Multimodal
Analgesia in the Management of Postoperative Pain in Patients Undergoing
Surgery under Spinal Anesthesia-Double Blind Study
Author(s): Madhu Mala, Prabha Parthasarathy and Raghavendra RaoMadhu Mala, Prabha Parthasarathy and Raghavendra Rao
Objective: To evaluate the efficacy and safety of opioid analgesic alone or in combination with a Non-steroidal Anti-inflammatory Drug (NSAID) in management of post-operative pain after regression of spinal anesthesia. Methods: In this double-blind study, 120 patients who underwent infra-umbilical surgeries under spinal anesthesia were chosen for the study and were randomly allocated into 4 groups of 30 each. Each group received Tramadol 100 mg or Pentazocine 30 mg or Tramadol 100 mg+Piroxicam 20 mg or Pentazocine 30 mg+Piroxicam 20 mg intramuscularly, 30 minutes after the end of the surgery. The primary efficacy end points were the total duration of post-operative analgesia and the intensity of pain relief in different groups, as assessed by VAS. Level of sedation and incidence of side effects were observed as secondary outcomes. Results: The mean VAS scores of the patients in Pentaz.. View More»
DOI:
10.4172/2155-6148.1000673