Journal of Drug Metabolism & Toxicology
Open Access

Raja S

Publications

• Research Article
  Effect of Manasamitra Vatakam Against Aluminium Induced Learning and Memory Impairment of Apoptosis in Rat ’ s Hippocampus and Cortex
  Author(s): Thirunavukkarasu SV, Jayanthi M, Raja S and Venkataraman S Thirunavukkarasu SV, Jayanthi M, Raja S and Venkataraman S
  
  The present study investigates neuronal cell death and neuroprotective effect of Manasamitra vatakam ( MMV ) against Aluminum (Al)-induced toxicity in rats. Aluminum and its salts extensively damaged nervous system and impaired learning and memory animals in neurodegenerative disease. In this study were conducted five groups, six animals in each group. In these study reveals Al caused neuronal apoptosis and cognitive dysfunction of animals brain regions (Hippocampus and Cortex) that could be restrain by treated with Manasamitra vatakam. MMV is a herbo-mineral formulation and prepared on the basis of Indian system of Ayurvedic medicine . These formulations using psychiatric treatment in Indian scenario, obviously tried for alternative treatment against Aluminium induced cognitive dysfunctions. It causes synthesis, release of neurotransmitter 5-hy.. View More»
  DOI: 10.4172/2157-7609.1000154

  Abstract PDF

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