Organic Chemistry: Current Research
Open Access
ISSN: 2161-0401
+44 1478 350008
ISSN: 2161-0401
+44 1478 350008
Rajendra D Patil
Casali Institute of Applied Chemistry, The Institute of Chemistry,
Jerusalem 91904
USA
Research Article
Chemoselective Reduction of Nitroarenes to Aromatic Amines with Commercial Metallic Iron Powder in Water Under Mild Reaction Conditions
Author(s): Rajendra D Patil, Yoel Sassona
Rajendra D Patil, Yoel Sassona
Novel, chemoselective, non-hazardous and mild reaction protocol was developed for an efficient reduction of nitroarenes to aromatic amines using “iron activated water”. Water function as a terminal hydrogen source without any external catalyst, acid, salts or base and in the absence of a solvent. In the course of the reaction, zero valent iron was oxidized to magnetite.
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DOI:
10.4172/2161-0401.1000154