ISSN: 2155-6148
Reona Sugimoto
Japan
Research Article
Efficacy of Intravenous Patient-Controlled Analgesia (IV-PCA) using Fentanyl Compared with IV-PCA Using Morphine after Abdominal Surgery: A Prospective Randomized Study
Author(s): Yukitoshi Niiyama, Nobuyoshi Matsuoka, Reona Sugimoto and Michiaki Yamakage
Yukitoshi Niiyama, Nobuyoshi Matsuoka, Reona Sugimoto and Michiaki Yamakage
Objective: To assess the efficacy and adverse effects of fentanyl intravenous (IV) patient-controlled analgesia (PCA) compared with morphine IV-PCA in patients after major abdominal surgery.
Methods: In a prospective, randomized, observer-blinded study, 40 patients with ASA physical status I-II who were scheduled to undergo major abdominal surgery. A standard general anesthetic was administered. Patients were randomly divided into two groups for 24h postoperatively: 1) Group F with fentanyl concentration of 25 μg/mL, background infusion of 25 μg/h, bolus of 25 μg, and lockout time of 10 min; and 2) Group M with morphine concentration of 1 μg/ml, no background infusion, bolus of 1 mg, and lockout time of 10 min. Numerical rating scale (NRS) pain scores at rest and on coughing and dose of additional PCA bolus and supplemental analg.. View More»
DOI:
10.4172/2155-6148.1000598