Journal of Medical Diagnostic Methods
Open Access

Richard E Mokhnach

Publications

• Short Communication
  The Advanced Bright-field Light Optical Polarization Microscopy: Novel Coupling Method for Detection of Micro Vesicles
  Author(s): Berezin AE, Mokhnach RE Berezin AE, Mokhnach RE
  
  Micro vesicles (MVs) are secreted as a component of secretome of various cells including stem cells, progenitors/ precursors and mature cells with different origin. MV are found to be a biological markers reflecting pathophysiological stages of disease, i.e. cardiovascular (CV) and metabolic diseases, autoimmune diseases, malignancy, infections and eclampsia. The fundamental effect of MV affects cell-to-cell cooperation, regulation of immune interrelations and transferring of several molecules. Therefore, there is a large body of evidence that confirmed the fact of number and phenotypes of MVs may be as a target for personal medical care as well as cargo for drug to the target cells. In this context, laboratory methods regarding purification of MV samples, determination of MVs, identification of origin of them and measure their concentration are fairly promising. The short communicati.. View More»
  DOI: 10.4172/2168-9784.1000254

  Abstract PDF

Relevant Topics