Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Robert G Hahn
Research Unit, Södertälje Hospital,
152 86 Södertälje
Sweden
Research Article
Fluid Retention is Alleviated by Crystalloid but Not by Colloid Fluid after Induction of General Anesthesia: An Open-Labeled Clinical Trial
Author(s): Robert G Hahn, Yuhong Li and Rui HeRobert G Hahn, Yuhong Li and Rui He
Background: Renal fluid conservation, which is possible to quantify by urine analysis, is often caused by dehydration. The present study aimed to determine whether such fluid retention could be reversed by crystalloid and/or colloid fluid during surgery. Methods: Urine colour, specific weight, osmolality and creatinine concentration were used to calculate a “fluid retention index” (FRI) in 108 patients undergoing major abdominal surgery. Urine was collected at baseline and after flow-guided fluid volume optimisation with hydroxyethyl starch 130/0.4 (n=86) or Ringer's lactate (n=22). The third sample was taken after one hour of surgery. Results: The mean preoperative FRI was 3.4 (SD 1.1) and did not change during the volume optimization. The FRI was unchanged from starch during the first hour of surgery, whereas it decreased from 3.6 to 2.9 in response to Ringer´s lac.. View More»
DOI:
10.4172/2155-6148.1000597