Journal of Medical Diagnostic Methods
Open Access

Rong H

Publications

• Review Article
  Diagnostic Availability (DA) based on Pythagorean Theorem as a Novel Index for Integrative Evaluation of Diagnostic Tests
  Author(s): He R, He SL He R, He SL
  
  Accurate diagnosis is the prerequisite for effective treatment of diseases. Various biostatistics indices have been used to evaluate the performance of diagnostic tests. The distribution of test results commonly shows a relatively fixed overlap between the diseased and non-diseased populations, and the two main properties of laboratory tests sensitivity (Se) and specificity (Sp) usually demonstrate an inverse relationship of each other. An inverse relationship is also seen in the two sides of a right triangle where the hypotenuse serves as an integrated functional index of the two sides, as reflected in the geometric equation Pythagorean Theorem (PT). We have developed a novel test performance index named diagnostic availability (DA) based on the theory of PT, which integrates and reflects the combined efficiency of Se and Sp. When Se and Sp were changing inversely as seen in the vast.. View More»
  DOI: 10.4172/2168-9784.1000244

  Abstract PDF

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