ISSN: 2155-6148
Roshana Amatya
Nepal
Research Article
Prevention of Spinal Anesthesia Induced Hypotension in Elderly: Comparison of Prophylactic Atropine with Ephedrine
Author(s): Shailendra Sigdel, Anil Shrestha and Roshana Amatya
Shailendra Sigdel, Anil Shrestha and Roshana Amatya
Background: Spinal anesthesia induced hypotension is more common and hazardous in elderly, as they have decreased physiological reserve and compromised blood supply to various vital organs. Reversal of the blunted reflexes of tachycardia following hypotension in elderly with atropine or ephedrine may help in prevention of hypotension.
Methodology: Present study is a prospective, randomized, double blind, controlled trial where sixty ASAPS I-II patients undergoing urological surgeries were assigned to receive either IV normal saline (placebo) or IV atropine 0.6 mg or IV ephedrine 12 mg one minute after induction of spinal anesthesia. Heart rate (HR), mean arterial pressure (MAP), requirement mephentermine and phenylephrine and side effects profile were studied were studied. Hemodynamic parameters were compared with baseline in each and among .. View More»
DOI:
10.4172/2155-6148.1000557