ISSN: 2167-0412
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Ruby K Koshy
The Oxford college of Pharmacy,
Bangalore, Karnataka
India
Research Article
Anti Hyperglycemic Activity of Elytraria Acaulis Lind. on Streptozotocin-Induced Diabetic Rats
Author(s): Ruby K Koshy, Raj Kapoor B and Mohammad Azamthulla
Ruby K Koshy, Raj Kapoor B and Mohammad Azamthulla
Aim of the present work is to evaluate the Anti-hyperglycemic activity of Elytraria acaulis Lind. on streptozotocininduced diabetic rats. Elytraria acaulis Lind. belongs to family Acanthaceae which is a small shrub, that grows in shady dry places. The whole plant is used for medicinal purposes. Diabetes was induced in rats by administering streptozotocin (60 mg/kg) intraperitonially. Animals were divided into five groups (n=6) receiving different treatments: Group I: vehicle (Control), Group II: diabetic (control), Groups III and IV: Elytraria acaulis Lind. extract treated (200 and 400 mg/kg, orally respectively) and Group V: standard anti diabetic drug glibenclamide (500 mcg/kg, orally). Blood serum was analyzed for the following biochemical parameters like blood glucose level, oral glucose tolerate test, body
weight and liver glycogen & glycated hemoglobin levels. Histopa.. View More»
DOI:
10.4172/2167-0412.1000103