ISSN: 2157-7595
+44 1478 350008
Ryota Matsuzawa
Japan
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Frailty and Survival in Patients with End-Stage Renal Disease
Author(s): Ryota Matsuzawa and Atsuhiko Matsunaga
Ryota Matsuzawa and Atsuhiko Matsunaga
Frailty is highly prevalent in patients with end-stage renal disease who require hemodialysis therapy. Frailty has been proposed by Fried and colleagues, and predicts poor outcomes in hemodialysis patients. Muscle weakness is a major component of frailty. We previously performed a single-center, prospective, observational, cohort study among 190 Japanese patients undergoing hemodialysis and examined the association of muscle weakness in lower extremity with survival. As a result, muscle weakness in the lower extremities had a significant negative effect on survival in these patients. Muscle weakness is reversibly activated by exercise training or physical therapy in patients undergoing hemodialysis. Therefore, exercise training for patients with end-stage renal disease could improve their prognosis via correction of muscle weakness. In this paper, we reviewed muscle weakness, which is.. View More»
DOI:
10.4172/2157-7595.1000227