Clinical & Experimental Cardiology
Open Access

S. Trivulzio

Publications

• Rapid Communication
  Identification of Factors Causing Sudden Coagulation in Patients with Acute Myocardial Infarction
  Author(s): Arnaldo Pinelli, S. Trivulzio, S. Brenna, V. Rosato, G. Galmozzi and G. Rossoni Arnaldo Pinelli, S. Trivulzio, S. Brenna, V. Rosato, G. Galmozzi and G. Rossoni
  
  Background: Coronary artery disease (CAD) evolving to acute myocardial infarction (AMI) is due to the thrombotic occlusion of coronary vessels in the presence of destabilized atheroma, rich in inflammatory cells secreting proteolytic enzymes that induce the development of thrombosis. The aim of this study was to analyse the plasma of AMI patients for the detection of proteases or factors that may cause fast coagulation. Methods: The patients were analysed for the presence in plasma of cardiac troponin T (c-TnT) or proteases as neutrophil gelatinase-associated lipocalin (NGAL) using ELISA method and matrix metalloproteinase-9 (MMP-9) utilising flow cytometry technique and interleukin-8 (IL-8) using flow cytometry methodology. Results: The presence of AMI was demonstrated by high levels of c-TnT; in comparison with controls the AMI patients displayed a significant increase in the values.. View More»
  DOI: 10.4172/2155-9880.1000202

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