Journal of Clinical and Experimental Ophthalmology
Open Access

Sabrina Bohnacker

Publications

• Research Article
  In Vitro Biocompatibility of Silicone Oil Siluron Xtra® on Porcine Retina in a Perfusion Culture System
  Author(s): Katharina L. Neuer, Sabrina Bohnacker, Nikolaus Feucht, Chris P. Lohmann, Mathias Maier Katharina L. Neuer, Sabrina Bohnacker, Nikolaus Feucht, Chris P. Lohmann, Mathias Maier
  
  Purpose: To examine the biocompatibility of Siluron Xtra® (Fluoron, Ulm, Germany), a silicone oil used as a vitreous substitute in vitreo-retinal surgery on porcine retinal tissue in vitro. Methods: Retinal tissue of 37 porcine eyes was immediately prepared post mortem and placed into Minucell perfusion systems (Minucell, Bad Abbach, Germany) to be perfused with liquid culture medium over a period of 4-8 days. 23 retinal tissue samples including retinal pigment epithelium (RPE) were covered by silicone oil (group 1) during the perfusion and compared to a control group of 7 samples (group 2) without silicone oil. Group 3 included 7 single RPE tissues without retinal tissue layer in direct contact with silicone oil, thus imitating a retinal tear, during the perfusion. The morphology of the retina and RPE was examined by light mic.. View More»
  DOI: 10.4172/2155-9570.1000679

  Abstract PDF

Relevant Topics