Anesthesia & Clinical Research
Open Access

Saeeda Haider

Publications

• Research Article
  Effectiveness of Midazolam in the Prevention of Etomidate Induced Myoclonus
  Author(s): Bushra Salim, Safia Zafar Siddiqui, Faisal Shamim and Saeeda Haider Bushra Salim, Safia Zafar Siddiqui, Faisal Shamim and Saeeda Haider
  
  Introduction: Etomidate, the imidazole derivative, is an intravenous anaesthetic induction agent, having stable hemodynamic profile, minimal respiratory side effects and histamine release. It is extremely useful in hemodynamically compromised patients. But the most common problem associated with its induction is myoclonus. Objective: To determine the effect of pretreatment with midazolam on the frequency of myoclonus after etomidate induction. Methods: Two hundred and fifty patients fulfilling the inclusion and exclusion criteria, scheduled for elective surgical procedures, were included. After all monitoring and intravenous access, the patients were given intravenous midazolam 0.05 mg/kg and after ninety seconds anesthesia induction was done with etomidate, and the myoclonic movements were noted for a minute after etomidate injection. The movement were recorded an.. View More»
  DOI: 10.4172/2155-6148.1000503

  Abstract PDF

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